Retro-Inverso Isomerization of Peptides: Side Reactions in the Synthesis of N,N'-Diacyl-1,1-diamino-2-phenylethane Derivatives

DOI: 10.1021/jo00179a014

Source and publish data:

Journal of Organic Chemistry p. 821 - 827 (1984)

Update date:2022-08-05

Topics:

Authors:

Chorev, Michael

MacDonald, Scott A.

Goodman, Murray

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00179a014

In general, the synthesis of retro-inverso peptides requires the formation of diacylated gem-diaminoalkyl structures.One way to prepare these gem-diaminoalkyl residues involves the Curtius rearrangement of the N-acylated amino acid hydrazides to the corre

Full text of DOI:10.1021/jo00179a014

Products guided by the article

Product name:1-Pyrrolidinecarboxylic acid, 2-(1,1-dimethylethoxy)-, phenylmethyl ester, (R)-

Cas No:88425-30-3

R&D Labs maybe for 88425-30-3

Pale Palm Imex

Contact:+36(21)2523420

Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
Wuhan Fortuna Chemical Co.,Ltd

website:http://www.fortunachem.com

Contact:86-27-59207850

Address:Add: Room 2015, No.2 Building, Kaixin Mansion No.107 Jinqiao Avenue, Wuhan, China
China Synchem Technology Co.,Ltd

website:http://www.cnsynchem.com

Contact:+86-0552-4929311

Address:No.217 Daqing Road
Chengdu Baishixing Science and Technology Industry Co., Ltd.

website:http://www.cd-bsx.com

Contact:+86-28-88531548

Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
UNION PHARMPRO CO.,LTD

Contact:18710867521(wechat)

Address:Rm10516,Galaxy Tech Building #2,No.25 Tangyan Rd,Hi-Tech Zone,Xi'an, China

Relevant to this article

Resolution and coupling of 1-(2′-hydroxy-1′-naphthyl)isoquinolines

Doi:10.1016/S0040-4020(01)00064-3
(2001)
Acetic acid-promoted, efficient, one-pot synthesis of 2,3- dihydroquinazolin-4(1H)-ones

Doi:10.1007/s00706-011-0494-6
(2011)
A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design

Doi:10.1016/j.ejmech.2017.12.085
(2018)
Design, synthesis, and biological evaluation of combretastatin nitrogen-containing derivatives as inhibitors of tubulin assembly and vascular disrupting agents

Doi:10.1016/j.bmc.2005.12.033
(2006)
Palladium catalyzed decarboxylative rearrangement of N-alloc indoles

Doi:10.1021/ol400110c
(2013)
One-Pot Synthesis of Pentafluorophenyl Sulfonic Esters via Copper-Catalyzed Reaction of Aryl Diazonium Salts, DABSO, and Pentafluorophenol

Doi:10.1021/acs.orglett.1c01056
(2021)

Article Doi