Highly stereoselective chelation-controlled allylation and deuteration of α-chiral α,α'-dialkoxy radicals

Article abstract of DOI:10.1246/cl.1996.845

Diastereoselectivity in the radical mediated allylation and deuteration reactions of β-chiral β-alkoxy-β-bromoaldehyde dimethyl acetals and a related alkoxy bromide were remarkably enhanced when the reactions were conducted in the presence of Lewis acid (MgBr₂·OEt₂ for allylation; MgI₂ for deuteration).