Synthesis of vinca alkaloids and related compounds. XVI. New route to the stereoselective synthesis of (+)-vincamine, (-)-vincamone and (+)-apovincaminic acid esters

Article abstract of DOI:10.1016/S0040-4020(01)88614-2

A stereoselective methods has been elaborated for the synthesis of oxime esters, from which, as common intermediates, (+)-apovincaminic acid esters, (+)-vincamine and (-)-vincamone can be prepared.