
Journal of Medicinal Chemistry p. 1936 - 1942 (1989)
Update date:2022-08-03
Topics:
Davis, Steven E.
Rauckman, Barbara S.
Chan, Joseph H.
Roth, Barbara
A series of nine 2,4-diamino-5-<6-(or 7-)quinolylmethyl>pyrimidines has been prepared by condensations of quinolinecarboxaldehydes with β-anilinopropionitriles, followed by treatment with guanidine.All compounds had basic or methoxy substituents at the 2-
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