2,4-Diamino-5-benzyloxypyrimidines and Analogues as Antibacterial Agents. 11. Quinolylmethyl Analogues with Basic Substituents Conveying Specificity

DOI: 10.1021/jm00128a041

Source and publish data:

Journal of Medicinal Chemistry p. 1936 - 1942 (1989)

Update date:2022-08-03

Topics:

Authors:

Davis, Steven E.

Rauckman, Barbara S.

Chan, Joseph H.

Roth, Barbara

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Article abstract of DOI:10.1021/jm00128a041

A series of nine 2,4-diamino-5-<6-(or 7-)quinolylmethyl>pyrimidines has been prepared by condensations of quinolinecarboxaldehydes with β-anilinopropionitriles, followed by treatment with guanidine.All compounds had basic or methoxy substituents at the 2-

Full text of DOI:10.1021/jm00128a041

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