2,4-Diamino-5-benzyloxypyrimidines and Analogues as Antibacterial Agents. 11. Quinolylmethyl Analogues with Basic Substituents Conveying Specificity

DOI: 10.1021/jm00128a041

Source and publish data:

Journal of Medicinal Chemistry p. 1936 - 1942 (1989)

Update date:2022-08-03

Topics:

Authors:

Davis, Steven E.

Rauckman, Barbara S.

Chan, Joseph H.

Roth, Barbara

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00128a041

A series of nine 2,4-diamino-5-<6-(or 7-)quinolylmethyl>pyrimidines has been prepared by condensations of quinolinecarboxaldehydes with β-anilinopropionitriles, followed by treatment with guanidine.All compounds had basic or methoxy substituents at the 2-

Full text of DOI:10.1021/jm00128a041

Products guided by the article

Product name:(Z)-2-(2-Dimethylamino-4-methyl-quinolin-6-ylmethyl)-3-phenylamino-acrylonitrile

Cas No:89446-22-0

R&D Labs maybe for 89446-22-0

Lonzeal Pharmaceuticals Co., Ltd.

website:http://www.lonzeal.com

Contact:+86-13381011962

Address:RM 801, Yue MOMA, No. 26 Anningzhuang Rd. Haidian District, Beijing, China
Shaanxi King Stone Enterprise Company Limited

Contact:86-29-88353805,13609285751

Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Zhejiang Sanmei Chemical Industry Co., Ltd

Contact:86-579-87633213

Address:Huchu Industrial Zone, Qingnian Rd., Wuyi County, Zhejiang Prov., China.
Taizhou Chenyi chemical co. LTD,

Contact:13736652831

Address:NO.273 SHANGHAI SOUTH STREET,LUQIAO DISTRICT,ZHEJIANG PROVINCE,CHINA.
puyang hongda shengdao new material co.,ltd.

Contact:+86-393- 4896278

Address:No.29 East Zhongyuan Road

Relevant to this article

SYNTHESIS AND UNAMBIGOUS CHARACTERIZATION OF OPTICALLY PURE (+)-4-DEMETHOXYADRIAMYCIN HYDROCHLORIDE

Doi:10.1246/cl.1984.2113
(1984)
Highly Chemoselective Palladium-Catalyzed Conjugate Reduction of α,β-Unsaturated Carbonyl Compounds with Silicon Hydrides and Zinc Chloride Cocatalyst

Doi:10.1021/ja00283a029
(1986)
Tripodal naphthalene ether ligand: Solid-state anion recognition and fluorescence studies

Doi:10.1016/j.molstruc.2007.08.016
(2008)
First enantioselective syntheses of (+)- and (-)-wilforonide by using chiral auxiliaries derived from the same chiral source.

Doi:10.1021/ol015722p
(2001)
Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) for the treatment of estrogen-dependent diseases

Doi:10.1016/j.bmc.2008.04.073
(2008)
A facile and effective synthesis of lipophilic 2,6-diketopiperazine analogues

Doi:10.1016/j.tet.2008.05.005
(2008)

Article Doi