Nucleophilic Displacement of N-Aryl and Heteroaryl Groups. Part 5. Conversion of 2-Aminopyridines into 2-Pyridones

DOI: 10.1039/P19830002623

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2623 - 2627 (1983)

Update date:2022-08-05

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Authors:

Katritzky, Alan R.

Awartani, Radi

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Article abstract of DOI:10.1039/P19830002623

2-Ethoxycarbonyl-1-(2-pyridyl)pyridinium cations (3) (easily prepared from 2-aminopyridine and the appropriate pyrylium salt) are converted by dilute NaOH at 25 deg C into 1-(substituted 2-pyridylcarbonyl)-2-pyridones (7).Compounds (7) are readily hydrolysed to 2-pyridones.

Full text of DOI:10.1039/P19830002623

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