2-Cyano-Δ3-piperideines. 12. Stereochemistry of Formation of N-Benzyl-2-cyano-Δ3-piperideines and Facile Isomerization on Alumina to 2-Cyano-Δ4-piperideines. A Potentially General Route to the Synthesis of 2,6-Disubstitute

DOI: 10.1021/jo00187a018

Source and publish data:

Journal of Organic Chemistry p. 2392 - 2400 (1984)

Update date:2022-09-26

Topics:

Authors:

Bonin, Martine

Romero, Jose Ricardo

Grierson, David S.

Husson, Henri-Philippe

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00187a018

The reaction of the piperideine N-oxides 1a-f with trifluoroacetic anhydride in CH2Cl2 at 0 deg C (Polonovski-Potier reaction) led to the formation of the N-benzyl-2-cyano-Δ³-piperideines 3a-f.Epimeric mixtures were obtained for the amino nitri

Full text of DOI:10.1021/jo00187a018

Products guided by the article

Product name:2-Pyridinecarbonitrile, 1,2,5,6-tetrahydro-4-methyl-1-(phenylmethyl)-

Cas No:89873-62-1

R&D Labs maybe for 89873-62-1

Tractus Company Limited

Contact:+852-8198 2399

Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
HaiNan Periwinkle Pharmaceutical Co.,Ltd.

website:http://www.cchpharm.com/en/index.html

Contact:020-82208978

Address:Gongye road,Wuzhishan city,HaiNan province
Anhui Hope-Chem Co., Ltd.

Contact:86-551-63540590

Address:No 1388 Furong Rd., Hefei, Anhui, China
waho int'l company

Contact:+86-579-85206992

Address:No 451 chouzhou north road ,room 1106 int'l business center , yiwu ,china
Shanghai Xinda Pharmaceuticals Co., Ltd.

Contact:86-21-33692333-8008

Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China

Relevant to this article

STEREOSELECTIVE REDUCTION OF 3-OXO AMIDES WITH ZINC BOROHYDRIDE

Doi:10.1016/S0040-4039(00)87875-2
(1983)
Facile synthesis of 1,3,7-trihydroxyxanthone and its regioselective coupling reactions with prenal: Simple and efficient access to osajaxanthone and nigrolineaxanthone F

Doi:10.1021/jo0606655
(2006)
Synthesis and optical properties of 6-substituted-β-cyclodextrin derivatives

Doi:10.2174/157017809790442899
(2009)
Design, synthesis, and antimicrobial activity of novel spiroisoxazolo[2,3- b[[1,2,4]thiadiazole-2,2-thiazolidine-4-ones and spiroisoxazolo[2,3-b[[1,2,4] oxadiazole-2, 2-thiazolidine-4-ones

Doi:10.1080/17415993.2012.703671
(2012)
SYNTHESIS AND PSYCHOTROPIC ACTIVITY OF PYRAZIDOLE ANALOGS

Doi:10.1007/BF00758834
(1984)
Gold(I)-catalyzed synthesis of dihydropyrans

Doi:10.1021/ja061344d
(2006)

Article Doi