A FORMAL TOTAL SYNTHESIS OF POLYOXIN J USING 4-O-BENZYL-2,3-O-ISOPROPYLIDENE-L-THREOSE AS A COMMON CHIRAL BUILDING BLOCK

Article abstract of DOI:10.1246/cl.1984.405

A convergent formal total synthesis of Polyoxin J was achieved.Two fragments, deoxypolyoxin C and 5-O-carbamoylpolyoxamic acid, were synthetized in a highly stereoselective manner from the common chiral building block, 4-O-benzyl-2,3-O-isopropylidene-L-th