Superelectrophilic-initiated C-H functionalization at the β-position of thiophenes: A one-pot synthesis of trans-stereospecific saddle-shaped cyclic compounds

Article abstract of DOI:10.1021/acs.joc.9b01233

Superelectrophilic-initiated direct C-H functionalization of thiophenes at the β-position was developed. A series of trans-stereospecific [2,1-a]-IF-thiophene-fused cyclic compounds (4) with saddle-shaped structure were prepared in 17-30% yields through a