Tetrahydropyrroloquinoxalines and Tetrahydropyrrolopyridopyrazines: Vascular Smooth Muscle Relaxants and Antihypertensive Agents

DOI: 10.1021/jm00378a039

Source and publish data:

Journal of Medicinal Chemistry p. 1743 - 1746 (1984)

Update date:2022-08-05

Topics:

Authors:

Abou-Gharbia, Magid

Freed, Meier E.

McCaully, Ronald J.

Silver, Paul J.

Wendt, Robert L.

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Article abstract of DOI:10.1021/jm00378a039

A series of tetrahydropyrrolo<1,2-a>quinoxalines and tetrahydropyrrolo<1,2-a>pyrido<3,2-a>pyrazines were synthesized and tested for their ability to relax K⁺-depolarized aortic smooth muscle and antihypertensive activity.It was shown that compo

Full text of DOI:10.1021/jm00378a039

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