Tetrahydropyrroloquinoxalines and Tetrahydropyrrolopyridopyrazines: Vascular Smooth Muscle Relaxants and Antihypertensive Agents

Article abstract of DOI:10.1021/jm00378a039

A series of tetrahydropyrrolo<1,2-a>quinoxalines and tetrahydropyrrolo<1,2-a>pyrido<3,2-a>pyrazines were synthesized and tested for their ability to relax K⁺-depolarized aortic smooth muscle and antihypertensive activity.It was shown that compo