
Bioorganic and Medicinal Chemistry p. 7862 - 7874 (2006)
Update date:2022-08-02
Topics:
Zhou, Longhu
Thakur, Chandar S.
Molinaro, Ross J.
Paranjape, Jayashree M.
Hoppes, Rieuwert
Jeang, Kuan-Teh
Silverman, Robert H.
Torrence, Paul F.
2′,5′-Oligoadenylate tetramer (2-5A) has been chemically conjugated to short HIV-1 Tat peptides to provide 2-5A-tat chimeras. Two different convergent synthetic approaches have been employed to provide such 2-5A-tat bioconjugates. One involved generation
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