
Journal of the American Chemical Society p. 3253 - 3266 (1985)
Update date:2022-07-29
Topics: Catalyst Enantioselective Synthetic route Total synthesis Diastereoselective Chiral Auxiliary Stereocontrolled (+)- Bicyclomycin
Williams, Robert M.
Armstrong, Robert W.
Dung, Jen-Sen
The completely regio- and stereocontrolled total synthesis of bicyclomycin (1) is described in 12 chemical steps.A new carbon-carbon bond-forming reaction on 1,4-dibenzyl- and 1,4-bis(p-methoxybenzyl)-3,6-bis(2'-thiopyridyl)-2,5-piperazinediones (10 and 4
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Doi:10.1021/jm00340a011
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