A FIRST AND GENERAL RULE TO NAPHTHYLISOQUINOLINE ALKALOIDS: THE TOTAL SYNTHESIS OF O-METHYL-TETRADEHYDRO-TRIOPHYOPHYLLINE

DOI: 10.1016/S0040-4039(01)81225-9

Source and publish data:

Tetrahedron Letters p. 2537 - 2540 (1984)

Update date:2022-08-04

Topics:

Authors:

Bringmann, Gerhard

Jansen, Johannes R.

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Article abstract of DOI:10.1016/S0040-4039(01)81225-9

The first total synthesis of a naphtylisoquinoline alkaloid is described.The required ortho selective mixed coupling of the alkaloid moieties 2 and 6 is achieved intramolecularly by the assistance of a reversibly thrown benzylether type auxiliary bridge.

Full text of DOI:10.1016/S0040-4039(01)81225-9

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