Bioorganic and Medicinal Chemistry Letters p. 2583 - 2586 (2002)
Update date:2022-08-04
Topics:
Gallant
Carriere
Chateauneuf
Denis
Gareau
Godbout
Greig
Juteau
Lachance
Lacombe
Lamontagne
Metters
Rochette
Ruel
Slipetz
Sawyer
Tremblay
Labelle
Potent and selective ligands for the human EP3 prostanoid receptor are described. Biaryl compounds bearing a tethered ortho substituted acidic moiety were identified as potent EP3 antagonists based on the SAR described herein. The binding affinity of key compounds on all eight human prostanoid receptors is reported.
View Morewebsite:http://www.herbpurify.com
Contact:0086-028-85249238
Address:Room709-C1,Incubator Building, Tianfu Life Science Park No.88,Keyuan Road,Gaoxin district,Chengdu City,Sichuan Prov,China
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd
website:http://www.jlpharms.com
Contact:+86-571-86982636
Address:Rm A606, Fuyi Center, jianqiao street, Jianggan Area
website:http://www.arromax.com
Contact:+86-0512-62959601 skype:aimmezhang
Address:Suite 401, Bldg A3, 218 Xinghu St.Suzhou Industrial Park 215123, P.R. China
Shanghai SMEC Trading Co., Ltd.
website:http://www.shanghaismec.com
Contact:+86-21-68811293
Address:ROOM 1101,NO.800 SHANGCHENG RD,SHANGHAI,CHINA
LianYunGang Chiral Chemical(CHINA) CO.,LTD
Contact:+86-518-83616958 +86-519-82884848
Address:LianYunGang Chemical Industry Park (JiangSu)
Doi:10.1016/j.biopha.2019.109781
(2020)Doi:10.1021/ja01056a027
(1964)Doi:10.1021/jm0607247
(2007)Doi:10.1021/jo062053q
(2007)Doi:10.1016/S0040-4020(01)93220-X
(1964)Doi:10.1246/cl.1984.1029
(1984)