Tetrahedron p. 1795 - 1802 (1984)
Update date:2022-08-04
Topics:
Shiozaki, Masao
Ishida, Noboru
Hiraoka, Tetsuo
Maruyama, Hiroshi
L-Threonine was transformed, stereospecifically, to a versatile β-lactam (5a) in 3 steps.This β-lactam was further converted to a key intermediate (25) for the synthesis of thienamycin and its biologically active analogues.Furthermore, the compound 5a was changed to iodides (18 and 23), cyanides (19 and 24), chloromethylketone (26) and aldehydes (30 and 31) which appear to have a latent potential as precursors for the syntheses of the carbapenems.
View MoreContact:+49-9398-993127
Address:Untertorstr. 27
Chiral Quest (Suzhou) Company Ltd
website:http://www.chiralquest.com
Contact:+86-0512-62956066
Address:B1/9, 218 Xinghu Street, Suzhou Industrial Park
Nanjing Fayekong Chemcial Co.,Ltd(expird)
Contact:86-25-58813444
Address:Rm 1503, Unit 1, Building 5, Zijinnanyuan, Nanjing, Jiangsu, China
Contact:+36(21)2523420
Address:Head office: 1102 Budapest, SZENT LASZLO TER 24/B. 1/1., HUNGARY / CHINA
Contact:86-25-84683399
Address:605, Phoenix Herui Plaza, No.389, South Taiping Road, Nanjing, China 210002
Doi:10.1039/jr9420000368
(1942)Doi:10.1021/ja062866w
(2006)Doi:10.1016/j.bmcl.2007.04.088
(2007)Doi:10.1016/S0040-4039(01)81418-0
(1984)Doi:10.1021/jo062254u
(2007)Doi:10.1016/0008-6215(84)85318-5
(1984)
