Tetrahedron p. 1795 - 1802 (1984)
Update date:2022-08-04
Topics:
Shiozaki, Masao
Ishida, Noboru
Hiraoka, Tetsuo
Maruyama, Hiroshi
L-Threonine was transformed, stereospecifically, to a versatile β-lactam (5a) in 3 steps.This β-lactam was further converted to a key intermediate (25) for the synthesis of thienamycin and its biologically active analogues.Furthermore, the compound 5a was changed to iodides (18 and 23), cyanides (19 and 24), chloromethylketone (26) and aldehydes (30 and 31) which appear to have a latent potential as precursors for the syntheses of the carbapenems.
View MoreZhejiang Genebest Pharmaceutical Co.,Ltd.
Contact:0086-571-63532866
Address:No.1 Jinboshi Rd Lishan Town Fuyang City Zhejiang Province China
Zhushan County Tianxin Pharmaceutical & Chemical Co., Ltd.
Contact:0086-719-4224892
Address:Tutang Road, Chengguan Town, Zhushan County, Hubei Province
Beijing Top Science biological technology co., LTD
Contact:+86-13439059536
Address:15-1705 jre three mile, Beijing 100000,CHINA
Daqing E-shine Chemical Co.,LTD
Contact:0086-024-31285112
Address:Hongweiyuan area, Ranghulu district
Hangzhou Neway Chemicals Co., Ltd.
Contact:+86-571-85095566
Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Doi:10.1039/jr9420000368
(1942)Doi:10.1021/ja062866w
(2006)Doi:10.1016/j.bmcl.2007.04.088
(2007)Doi:10.1016/S0040-4039(01)81418-0
(1984)Doi:10.1021/jo062254u
(2007)Doi:10.1016/0008-6215(84)85318-5
(1984)
