Preliminary studies on the transformation of nitrosugars into branched chain iminosugars: Synthesis of 1,4-dideoxy-4-C-hydroxymethyl-1,4-imino- pentanols

Article abstract of DOI:10.1021/ol062887v

A novel promising strategy for the transformation of nitrosugars into branched pyrrolidines, based on double Henry reaction with formaldehyde followed by reductive ring closure, allowed the first enantiospecific synthesis of a 4-C-hydroxymethyl branched d