An Easy Route to Synthesize 1,5-Arylodiazepin-2-ones

Article abstract of DOI:10.1016/S0040-4039(00)74410-8

A series of 1,5-arylodiazepin-2-ones is prepared by the condensation of the approptiate o-β-arylenediamines with β-ketoesters in xylene under microwave irradiation.The reaction time is shortened to 10 mn, and the products are obtained in high yields.No by products are observed.Specific effects of microwaves are evidenced as no reaction occurs by classical heating in same conditions. - Key Words: Condensation; Microwave; 1,5-Arylodiazepin-2-ones.