Chemistry Letters p. 1573 - 1576 (1984)
Update date:2022-09-26
Topics:
Fuchikami, Takamasa
Yamanouchi, Akiko
Suzuki, Yasuyuki
Diethyl fluoromalonate was prepared in one-pot from chlorotrifluoroethene via trifluoroacrylic acid lithium salt in 79percent yield.Diethyl fluoromalonate was easily converted to 5-fluoro-6-chlorouracils, reductions of which gave 5-fluorouracils in good yields.
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