European Journal of Medicinal Chemistry p. 375 - 379 (1991)
Update date:2022-08-04
Topics:
Oliver
Dekker
Snyckers
The synthesis and biological activity of a series of pentacyclo[5.4.0.02,6.03,10.05,9]undecyl-8-amino derivatives are described. The activity of the compounds to antagonize the reserpine induced catatonia (anticataleptic) and their ability to reduce the oxotremorine induced tremor and salivation were determined in order to evaluate their potential as anti-Parkinson agents. Promising anticataleptic and mild to weak anticholinergic activities were observed for these compounds. The influence of substituents is discussed.
View MoreMedicalChem(Yancheng)Manuf.Co.,Ltd.
Contact:+86-515-84383366
Address:Touzeng BinHai, YanCheng City, JiangSu Province, China
Synchem Pharma Co.,Ltd(expird)
Contact:+0086-21-61984905-1
Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China
Contact:+86-577-65618087-605
Address:Room 402, Unit 4 Xinhu Bldg. Waitan Ruian City, Zhejiang China.
Contact:0572-2722882
Address:1201,F3,xinghuibandao,
Wuhan Better Organic Technology Inc.
Contact:13307163183
Address:Wuhan Economic&Technology Development Zone, Hubei
Doi:10.1039/b617549j
(2007)Doi:10.1021/jo01068a021
(1961)Doi:10.1016/j.bmcl.2007.02.002
(2007)Doi:10.1080/10426507.2020.1759063
(2020)Doi:10.1021/acs.jmedchem.9b00778
(2019)Doi:10.1021/ol070694h
(2007)
