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Long-Acting Dihydropyridine Calcium Antagonists. 4. Synthesis and Structure-Activity Relationships for a Series of Basic and Nonbasic Derivatives of 2--1,4-dihydropyridine Calcium Antagonists

DOI: 10.1021/jm00164a019

Source and publish data:

Journal of Medicinal Chemistry p. 585 - 591 (1990)

Update date:2022-08-02

Topics:

Authors:

Alker, DavidAlker, David

Campbell, Simon F.Campbell, Simon F.

Cross, Peter E.Cross, Peter E.

Burges, Roger A.Burges, Roger A.

Carter, Anthony J.Carter, Anthony J.

Gardiner, Donald G.Gardiner, Donald G.

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Article abstract of DOI:10.1021/jm00164a019

The preparation of a series of 1,4-dihydropyridines (DHPs) which have polar, acyclic, nonbasic substituents on an ethoxymethyl chain at the 2-position is described.In addition, in order to assess the effects of incorporating a basic center into DHPs of th

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Full text of DOI:10.1021/jm00164a019

Products guided by the article

Product name:1-<2-<<4-(2-chlorophenyl)-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyrid-2-yl>methoxy>ethyl>-2-cyano-3-<2-(dimethylamino)ethyl>guanidine

Cas No:93848-91-0

93848-91-0

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