Long-Acting Dihydropyridine Calcium Antagonists. 4. Synthesis and Structure-Activity Relationships for a Series of Basic and Nonbasic Derivatives of 2--1,4-dihydropyridine Calcium Antagonists

DOI: 10.1021/jm00164a019

Source and publish data:

Journal of Medicinal Chemistry p. 585 - 591 (1990)

Update date:2022-08-02

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Authors:

Alker, David

Campbell, Simon F.

Cross, Peter E.

Burges, Roger A.

Carter, Anthony J.

Gardiner, Donald G.

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Article abstract of DOI:10.1021/jm00164a019

The preparation of a series of 1,4-dihydropyridines (DHPs) which have polar, acyclic, nonbasic substituents on an ethoxymethyl chain at the 2-position is described.In addition, in order to assess the effects of incorporating a basic center into DHPs of th

Full text of DOI:10.1021/jm00164a019

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