Thromboxane Synthetase Inhibitors (TXSI). Design, Synthesis, and Evaluation of a Novel Series of ω-Pyridylalkenoic Acids

DOI: 10.1021/jm00381a005

Source and publish data:

Journal of Medicinal Chemistry p. 287 - 294 (1985)

Update date:2022-08-05

Topics:

Authors:

Kato, Kaneyoshi

Ohkawa, Shigenori

Terao, Shinji

Terashita, Zen-ichi

Nishikawa, Kohei

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Article abstract of DOI:10.1021/jm00381a005

A novel series of ω-pyridylalkenoic acids has been prepared by applying the Wittig reaction.Modifications were made in the ω-aryl moiety, the alkylene chain length, the α-methylene group adjacent to the carbonyl group, and the carboxyl group in the molecu

Full text of DOI:10.1021/jm00381a005

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