
Journal of Medicinal Chemistry p. 4139 - 4151 (1993)
Update date:2022-08-06
Topics: Synthesis Antimicrobial Evaluation
Bucsh, Ruth A.
Domagala, John M.
Laborde, Edgardo
Sesnie, Josephine C.
A series of 6-fluoroquinolone- and 6-fluoro-1,8-naphthyridone-3-carboxylic acids possessing a <3-amino (or aminomethyl)-4-aryl (or cyclopropyl)-1-pyrrolidinyl> group at C-7 were synthesized and evaluated for their antimicrobial activity. The effect of the
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