Synthesis of fluorinated acyclic nucleoside phosphonates with 5-azacytosine base moiety

DOI: 10.1016/j.tet.2019.130529

Source and publish data:

Tetrahedron (2019)

Update date:2022-08-04

Topics:

Authors:

Pomeisl, Karel

Kre?merová, Marcela

Pohl, Radek

Snoeck, Robert

Andrei, Graciela

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Article abstract of DOI:10.1016/j.tet.2019.130529

With respect to the strong antiviral activity of (S)-1-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine various types of its side chain fluorinated analogues were prepared. The title compound, (S)-1-[3-fluoro-2-(phosphonomethoxy)propyl]-5-azacytosine

Full text of DOI:10.1016/j.tet.2019.130529

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