Dibenzoxepinalkanoic Acids as Nonsteroidal Antiinflammatory Agents. 4. Synthesis and Evaluation of 4-(4,10-Dihydro-10-oxothienobenzoxepin-8-yl)butanol and -butyric Acid and Related Derivatives

DOI: 10.1021/jm00369a023

Source and publish data:

Journal of Medicinal Chemistry p. 372 - 376 (1984)

Update date:2022-07-29

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Authors:

Martin, Lawrence L.

Setescak, Linda L.

Spaulding, Theodore C.

Helsley, Grover C.

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Article abstract of DOI:10.1021/jm00369a023

4,10-Dihydro-10-oxothieno<3,2-c><1>benzoxepin-8-acetic acid (6) was previously reported as a potent antiinflammatory-analgesic agent characterized by an impressive therapeutic ratio in comparison with indomethacin.With the goal of finding compounds that m

Full text of DOI:10.1021/jm00369a023

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