Syntheses of the eastern halves of ritterazines B, F, G, and H, leading to reassignment of the 5,5-spiroketal stereochemistry of ritterazines B and F

DOI: 10.1021/ja0705487

Source and publish data:

Journal of the American Chemical Society p. 6589 - 6598 (2007)

Update date:2022-08-03

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Authors:

Phillips, Scott T.

Shair, Matthew D.

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Article abstract of DOI:10.1021/ja0705487

The ritterazine class of natural products comprises 26 compounds - all of which are spiroketal-containing steroidal heterodimers - that inhibit the proliferation of cultured human cancer cell lines with IC₅₀ values in the low nanomolar range. L

Full text of DOI:10.1021/ja0705487

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