Tetrahedron Letters p. 7111 - 7114 (1997)
Update date:2022-08-05
Topics:
Hird, Nicholas W.
Irie, Kazuyuki
Nagai, Katsunori
A series of resin-bound 4-substituted-2-aminobutadienes have been synthesised via Wittig reaction with polymer supported 2-(N-piperazino)prop-1-enyl-1-triphenylphosphonium bromide. The use of piperazine provides a readily cleavable enamine linker for attachment of ketones that is compatible with anion chemistry.
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