Synthesis and antiviral activity of 2 and 3-substituted imidazo[1,2- a]pyrimidine

Article abstract of DOI:10.1080/15257779508012425

Synthesis of acyclo-C-nucleoside derivatives in the imidazo[1,2- a]pyrimidine series was reported. None of the evaluated compounds showed appreciable antiviral activity.

Full text of DOI:10.1080/15257779508012425

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Nucleosides and Nucleotides
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Synthesis and Antiviral Activity of 2 and
3-Substituted Imidazo[1,2-a]pyrimidine
A. Gueiffier a , Y. Blache a , J. P. Chapat a , A. Elhakmaoui b , E. M.
Essassi b , G. Andrei c , R. Snoeck c , E. De Clercq c , O. Chavignon d
J. C. Teulade d & F. Fauvelle e
,
a Laboratoire de Chimie Organique Pharmaceutique, URA-CNRS
1111, Facultéa de Pharmacie, 15 Avenue Charles Flahault, 34060,
Montpellier, France
b Laboratoire de Chimie Organique, Universitéa Mohammed V,
Facultéa des Sciences, Rabat, Maroc
c Katholieke Universiteit Leuven, Rega Institute for Medical
Research, Minderbroedersstraat, 10, B-3000, Leuven, Belgique
d Déapartement de Chimie Structurale, Facultéa de Pharmacie,
Université d'Auvergne, 63001, Clermont-Ferrand, France
e Centre de Recherches du Service de Santéa des Arméaes, Unitéa
de Biophysique, B. P. 87, 38702, La, Tronche Cedex, France
Version of record first published: 16 Feb 2007.
To cite this article: A. Gueiffier, Y. Blache, J. P. Chapat, A. Elhakmaoui, E. M. Essassi, G. Andrei,
R. Snoeck, E. De Clercq, O. Chavignon, J. C. Teulade & F. Fauvelle (1995): Synthesis and Antiviral
Activity of 2 and 3-Substituted Imidazo[1,2-a]pyrimidine, Nucleosides and Nucleotides, 14:3-5,
551-554
To link to this article: http://dx.doi.org/10.1080/15257779508012425
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