Impact of the 3,6,9-trioxadecyloxy group on desazadesferrithiocin analogue iron clearance and organ distribution

DOI: 10.1021/jm070214s

Source and publish data:

Journal of Medicinal Chemistry p. 3302 - 3313 (2007)

Update date:2022-07-30

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Authors:

Bergeron, Raymond J.

Wiegand, Jan

Bharti, Neelam

Singh, Shailendra

Rocca, James R.

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Article abstract of DOI:10.1021/jm070214s

The impact of introducing a 3,6,9-trioxadecyloxyl group at various positions of the desazadesferrithiocin (DADFT) aromatic ring on iron clearance and organ distribution is described. Three DADFT polyethers are evaluated: (S)-4,5-dihydro-2-[2-hydroxy-4-(3,

Full text of DOI:10.1021/jm070214s

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