Benzothiopyranoindazoles, a new class of chromophore modified anthracenedione anticancer agents. Synthesis and activity against murine leukemias

DOI: 10.1021/jm00403a009

Source and publish data:

Journal of Medicinal Chemistry p. 1527 - 1539 (1988)

Update date:2022-07-29

Topics: Synthesis Anticancer agents Chromophore

Authors:

Hollis Showalter

Angelo Angelo

Berman Berman

Kanter Kanter

Ortwine Ortwine

Ross-Kesten

Sercel Sercel

Turner Turner

Werbel Werbel

Worth Worth

Elslager

Leopold Leopold

Shillis Shillis

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00403a009

The synthesis of the benzothiopyranoindazoles (3), a new class of chromophore modified anthracenediones related to mitoxantrone (1), is described. In this structural class the quinone moiety, which is believed to be responsible for the cardiotoxicity of t

Full text of DOI:10.1021/jm00403a009

Products guided by the article

Product name:6-chloro-2-<(4-methoxyphenyl)thio>-3-nitrobenzoic acid

Cas No:94636-20-1

R&D Labs maybe for 94636-20-1

Wuhan Shengmao Corp

website:http://www.shengmaochem.com

Contact:86-27-82853423, 82819281

Address:Rm 202, A Unit Huaqiao Building No. 2, Lihuangpi Road, Wuhan, China
SHANDONG QINGYUNCHANGXIN CHEMICAL SCIENCE-TECH CO.,LTD

Contact:86-21-60560171

Address:1689Donghuan Rade,Qingyun County, Dezhou City, Shandong,China
Hefei TNJ chemical industry co.,ltd

website:https://www.tnjchem.com

Contact:+86-551-65418695

Address:B911 Xincheng Business Center, Qianshan Road, Hefei Anhui China
KindChem Co.,Ltd,

Contact:+86-25-85281586

Address:13F,Bld2#,South of Longpan Road
Taixing Shenfeng Chemical Co., Ltd.

Contact:+86-523-87117033, 87117666

Address:4# Yinsanlu, Huangqiao town, Taixing, Jiangsu, China.

Relevant to this article

Stereoselective construction of fluorinated indanone derivatives via a triple cascade Lewis acid-catalyzed reaction

Doi:10.1039/b702114c
(2007)
Impact of Phosphorothioate Chirality on Double-Stranded siRNAs: A Systematic Evaluation of Stereopure siRNA Designs

Doi:10.1002/cbic.201900630
(2020)
Effects of solvent and temperature on the 1,4-asymmetric induction in the diastereoselective hydrogenation of dehydrodipeptides

Doi:10.1246/bcsj.62.3508
(1989)
Thiotetrazole alkynylacetanilides as potent and bioavailable non-nucleoside inhibitors of the HIV-1 wild type and K103N/Y181C double mutant reverse transcriptases

Doi:10.1016/j.bmcl.2007.06.012
(2007)
SYNTHESIS OF 2'-DEOXYRIBONUCLEOSIDES OF ALLOPURINOL BY PHASE-TRANSFER GLYCOSYLATION

Doi:10.1016/S0040-4039(01)91106-2
(1984)
Coumarins by Direct Annulation: β-Borylacrylates as Ambiphilic C₃-Synthons

Doi:10.1002/anie.202012099
(2021)

Article Doi