Journal of labelled compounds and radiopharmaceuticals p. 321 - 324 (1978)
Update date:2022-09-26
Topics:
Teng
Bruce
An improved method for small scale synthesis of phenylephrine hydrochloride is described. 5-[3-(phenylmethoxy)phenyl]-2-oxazolidinone was methylated with dimethylsulfate-methyl-3H3. The resulting compound was converted to phenylephrine hydrochloride by alkaline hydrolysis followed by hydrogenolysis. The radiochemical yield was over 50% based on dimethyl sulfate.
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Contact:+86-592-3216205
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