One-Step Synthesis of 2- and 4-Nitrobenzyl Cyanides

DOI: 10.1055/s-1987-27989

Source and publish data:

Synthesis p. 514 - 515 (1987)

Update date:2022-08-04

Topics:

Authors:

Kalir, Asher

Mualem, Rivka

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Article abstract of DOI:10.1055/s-1987-27989

2-Nitrobenzyl cyanide (2) and analogs were obtained in fair to good yields by reacting the corresponding bromides with sodium cyanide and hydrogen cyanide in dimethyl sulfoxide.Hydrogen cyanide could be generated in situ from an excess of sodium cyanide and trifluoroacetic acid.

Full text of DOI:10.1055/s-1987-27989

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