Enantiospecific synthesis of optically pure (3S)-hydroxy esters by the stereocontrolled yeast reduction of α-sulfenyl-β-ketoesters

Article abstract of DOI:10.1016/S0040-4039(01)91125-6

Stereocontrol in Baker's yeast reduction of β-ketoesters was successfully achieved by introducing the sulfenyl group at the α-position of the esters to afford optically pure (S)-β-hydroxy esters.