A new approach for the synthesis of fused pyrroles. The synthesis of acyl substituted pyrrolo[1,2-x]azines

Article abstract of DOI:10.1002/jhet.5570300621

N-Acetonyl- and N-phenacyl quaternary salts of α-methyl substituted heterocycles 16, 17, 21, 23 and 26 were converted with DMFDMA into the corresponding 3-acylpyrrolo[1,2-a]pyridine 18, 7-benzoylpyrrolo[1,2- c]pyrimidine 22, and 6-benzoylpyrrolo[1,2-a]pyrazine derivatives 24 and 27. A concurrent reaction produced methyl and phenyl substituted pyrrolo[1,2- x]azines 19, 20, 25 and 28.