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Synthesis and biological activity of 1α-fluoro-25-hydroxyvitamin D3

DOI: 10.1248/cpb.32.3525

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3525 - 3531 (1984)

Update date:2022-09-26

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Authors:

OhshimaOhshima

SaiSai

TakatsutoTakatsuto

IkekawaIkekawa

KobayashiKobayashi

TanakaTanaka

DeLucaDeLuca

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Article abstract of DOI:10.1248/cpb.32.3525

trans Diaxial opening with potassium hydrogen difluoride of the 1β,2β-epoxy-3β-ol derived from cholenic acid gave the 1α-fluoro-2β,3β-diol derivative. Construction of the 25-hydroxy cholesterol side chain and deoxygenation of the 2β-hydroxy group afforded

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Full text of DOI:10.1248/cpb.32.3525

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Products guided by the article

Product name:1α-fluoro-25-hydroxyvitamin D3 3-acetate

Cas No:95511-62-9

95511-62-9

R&D Labs maybe for 95511-62-9

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