Steroids p. 219 - 224 (1984)
Update date:2022-09-26
Topics:
Hylarides, Mark D.
Leon, Alberto A.
Mettler, Fred A.
The synthesis of the previously unknown 1-chloroestradiol (1), is reported.Addition of N-chlorosuccinimide/NaI in dioxane to 4-aminoestradiol 3-methyl ether (2), resulted in exclusive chlorination of the 1-position.Subsequent deamination and demethylation afforded 1 in good yields.
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Doi:10.1021/jm00383a018
(1985)Doi:10.1016/j.bmcl.2009.11.087
(2010)Doi:10.1002/anie.200702278
(2007)Doi:10.1016/S0040-4039(00)81777-3
(1983)Doi:10.1039/d0nj03425h
(2020)Doi:10.1016/j.tet.2007.09.032
(2007)
