A concise approach for the synthesis of bitungolides: Total syntheses of (-)-bitungolide B & e

Article abstract of DOI:10.1039/c4ob00250d

The first total synthesis of (-)-bitungolide B and a second-generation total synthesis of (-)-bitungolide E are described. The cornerstone of the approach comprises a convergent and flexible route involving Brown crotylation, highly diastereoselective sub