27. Synthesis of a building block for a nucleic-acid analog with a chiral, flexible peptide backbone

Article abstract of DOI:10.1002/hlca.19960790128

We present here a nine-step synthesis of the thymine-containing amino ester 1, starting from commercially available methyl N-[(tert-butoxy)carbonyl]-L-seritiate. Amino ester 1 is considered as a building block for the preparation of a new nucleic-acid ana