AN EFFICIENT SYNTHESIS OF 3α-HYDROXY-5α-PREGNA-9(11),16-DIEN-20-ONE

DOI: 10.1016/S0039-128X(84)90120-X

Source and publish data:

Steroids p. 491 - 498 (1984)

Update date:2022-08-04

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Authors:

Kim, Wan Joo

Kim, Jung Ho

Shim, Sang Chul

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Article abstract of DOI:10.1016/S0039-128X(84)90120-X

3α-Hydroxy-5α-pregna-9(11),16-dien-20-one (6) was synthesized for the first time from the commercially available 16,17α-epoxy-3β-hydroxy-5-pregnen-20-one (1) in several steps.The key step involves a remote chlorination reaction utilizing m-iodobenzoate gr

Full text of DOI:10.1016/S0039-128X(84)90120-X

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