Stereocontrol of stereogenic centres para on a benzene ring using the SE2″ reaction of a pentadienylsilane

DOI: 10.1039/p19960001197

Source and publish data:

Journal of the Chemical Society. Perkin Transactions 2 (2001) p. 1197 - 1203 (1996)

Update date:2022-07-30

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Authors:

Fleming, Ian

Leslie, Colin P.

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Article abstract of DOI:10.1039/p19960001197

The pentadienylsilane 9 and the dimethyl acetal 2 of isobutyraldehyde react with high (80:20) anti stereospecificity to give largely the diene 10a, which was converted into the Para-disubstituted benzene 11a, having 1,6-related stereogenic centres.

Full text of DOI:10.1039/p19960001197

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