Synthesis and Some Pharmacological Properties of 18 Potent O-Alkyltyrosine-Substituted Antagonists of the Vasopressor Responses to Arginine-Vasopressin

DOI: 10.1021/jm00148a019

Source and publish data:

Journal of Medicinal Chemistry p. 1485 - 1491 (1985)

Update date:2022-08-03

Topics:

Authors:

Manning, Maurice

Lammek, Bernard

Bankowski, Krzysztof

Seto, Janny

Sawyer, W. H.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00148a019

Using the Merrifield solid-phase method, we have synthesized 18 new 2-O-alkyltyrosine-substituted analogues (where alkyl = methyl and ethyl) of the arginine-vasopressin (AVP) vasopressor antagonists <1-deaminopenicillamine>arginine-vasopressin (dPAVP), <1

Full text of DOI:10.1021/jm00148a019

Products guided by the article

Product name:<1-deaminopenicillamine,2-O-ethyltyrosine,4-valine>arginine-vasopressin

Cas No:97690-60-3

R&D Labs maybe for 97690-60-3

Shijiazhuang Frontierchem Co., Ltd.

Contact:+86-311-89271196

Address:4-4-202 No.15 Biandian Street,Shijiazhuang
Wuhan Yitongtai Science and Technology Co.,Ltd.

Contact:+86-27-88933550

Address:27th Fl. Bldg. 1, Shuian International Mansion, Heping Ave, Wuhan, Hubei, China
Hubei Danao Pharmaceutical Co.,Ltd.

website:http://www.danaopharm.com

Contact:+86-719-5251167

Address:Fandan Road,Danjiangkou,Hubei
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.

Contact:+86-576-87501888 / 87501988

Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
Quzhou Ruiyuan chemical Co., Ltd

Contact:+86-570-3039321/3039361/3039308

Address:18# Huayang Road,Quzhou High-tech Industrial Park, Zhejiang China.

Relevant to this article

Doi:10.1021/ja00305a048
(1985)
6,7-Secoandrostane derivatives

Doi:10.1135/cccc19850962
(1985)
An Improved Synthesis of Methyl 7-(2-Hydroxy-5-oxo-1-cyclopentenyl)heptanoate

Doi:10.1246/bcsj.61.993
(1988)
Oxonium Ion Elektrophiles: Synthesis of the Hypotensive Oudenone.

Doi:10.1021/jo00220a032
(1985)
BAUSPLENDIN, A DIMETHYLENEDIOXYFLAVONE FROM BAUHINIA SPLENDENS

Doi:10.1016/S0031-9422(00)83187-8
(1985)
Asymmetric Synthesis Using Chiral Lithium Alkoxytrialkylaluminates: Obtention of (2S)-2-Hydroxy-2-phenyl-4-methylpentanoic Acid with 85percent Optical Purity

Doi:10.1021/jo00221a016
(1985)

Article Doi