Journal of the Chemical Society. Chemical communications p. 353 - 354 (1985)
Update date:2022-07-30
Topics:
Bates, Hans Aaron
Smilowitz, Lloyd
Rosenblum, Stuart B.
A highly efficient stereospecific synthesis of the biotin precursor (3aα,6aα)-1,3-dibenzylhexahydro-1H-thieno<3,4-d>imidazol-2(3H)-one 1,1-dioxide (6) is reported, by the cyclisation of the urea (5), which was obtained from the amine (4), (4) itself being prepared by the reaction of the dibromide (2) with benzylamine.
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Doi:10.1021/jo00219a053
(1985)Doi:10.1021/jo00392a007
(1987)Doi:10.1021/om00130a014
(1985)Doi:10.1002/cctc.201402548
(2014)Doi:10.1016/S0040-4039(00)98338-2
(1985)Doi:10.1002/hlca.19560390202
(1956)
