Angiotensin Converting Enzyme Inhibitors: Structure-Activity Profile of 1-Benzazepin-2-one Derivatives

DOI: 10.1021/jm00149a010

Source and publish data:

Journal of Medicinal Chemistry p. 1603 - 1606 (1985)

Update date:2022-08-03

Topics:

Authors:

Stanton, James L.

Watthey, Jeffrey W. H.

Desai, Mahesh N.

Finn, Barbara M.

Babiarz, Joseph E.

Tomaselli, Hollis C.

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Article abstract of DOI:10.1021/jm00149a010

The preparation of a series of 3-amino-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetic acid derivatives 5a-y by reductive amination of 2,3,4,5-tetrahydro-1H-1-benzazepine-2,3-dione (7) with L-amino acid derivatives is described.The compounds were teste

Full text of DOI:10.1021/jm00149a010

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