Chemistry of Heterocyclic Compounds p. 892 - 897 (1988)
Update date:2022-08-03
Topics:
Tochilkin, A. I.
Kovel'man, I. R.
Prokof'ev, E. P.
Gracheva, I. N.
Levinskii, M. V.
The bromination of quinoline and substituted quinolines with N-bromosuccinimide in concentrated H2SO4 takes place exclusively in the homocyclic part.Bromo-substituted quinolines can be obtained by this method.The bromination products were identified by PMR spectroscopy.The differences among the mono-, di-, and trisubstituted (in the benzene ring) compounds were established on the basis of the type of spectrum of the protons of the homocyclic part of the molecule.The compositions of the reaction mixtures were studied by GLC.
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