A facile synthesis of 3-substituted 5-oxo-1,2,4-thiadiazoles from amidoximes

DOI: 10.1002/jhet.5570370603

Source and publish data:

Journal of Heterocyclic Chemistry p. 1419 - 1423 (2000)

Update date:2022-09-26

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Authors:

Kohara Kohara

Kubo Kubo

Imamiya Imamiya

Naka Naka

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Article abstract of DOI:10.1002/jhet.5570370603

The reaction of amidoximes 1 with 1,1′-thiocarbonyldiimidazole (TCDI) followed by treatment with silica gel or boron trifluoride diethyl etherate (BF₃·OEt₂) provided 3-substituted 4,5-dihydro-5-oxo-1,2,4-thiadiazoles 2 in moderate yi

Full text of DOI:10.1002/jhet.5570370603

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