
Journal of the American Chemical Society p. 7515 - 7518 (1985)
Update date:2022-08-02
Topics: Characterization Yield NMR spectroscopy Catalyst Chromatography Total synthesis Stereocontrolled
Nicolau, K. C.
Veale, C. A.
Webber, S. E.
Katerinopoulos, H.
A stereocontrolled total synthesis of lipoxin A and a number of its isomers is reported.The strategy involves Sharpless asymmetric epoxidation and pinylborane asymmetric reduction to build the hydroxy-bearing stereocenters and a Wittig-type as well as a P
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