Antitumor activity of bis(diphenylphosphino)alkanes, their gold(i) coordination complexes, and related compounds

DOI: 10.1021/jm00395a004

Source and publish data:

Journal of Medicinal Chemistry p. 2181 - 2190 (1987)

Update date:2022-07-30

Topics: Antitumor Coordination Activity Experimental Related compounds

Authors:

Mirabelli

Hill Hill

Faucette

McCabe McCabe

Girard Girard

Bryan Bryan

Sutton Sutton

O'Leary Bartus

Crooke Crooke

Johnson Johnson

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Article abstract of DOI:10.1021/jm00395a004

Bisphosphines related to bis(diphenylphosphino)ethane (dppe) and their gold complexes are described that are active in a spectrum of transplantable tumor models. When administered ip on days 1-5 at its maximally tolerated dose (MTD) of 40 μmol/kg, dppe re

Full text of DOI:10.1021/jm00395a004

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