Electronic probing of ketone catalysts for asymmetric epoxidation. Search for more robust catalysts

Article abstract of DOI:10.1021/ol000385q

Equation presented Ketones with a fused oxazolidinone were synthesized and investigated to determine the electronic effect of the substituents at α-positions of ketone catalysts on the Baeyer-Villiger oxidation and catalytic properties for asymmetric epoxidation. These new ketones give high yields and ee's with only 1 5 mol % catalyst. The current studies further show that the electronic effect is very important for the kitone-catalyzed epoxidation.