Efficient reduction of aryl azides and aryl nitro compounds to their corresponding amines with sulfurated calcium borohydride Ca(BH2S3)2. A new modified borohydride agent

Article abstract of DOI:10.1080/00397910008087360

Ca(BH₂S₃)₂ is easily prepared by metathetical reaction between NaBH₂S₃ and CaCl₂ in THF. Ca(BH₂S₃)₂ is much more stable than NaBH₂S₃ therefore, is a more practical reagent. Sulfurated calcium borohydride can easily reduce aryl nitro and aryl azido functions to their amines in high yields in refluxing THF. Reduction of nitro groups is accompanied with regioselectivity. Very high chemoselectivity is also observed for the reduction of an azido functional group in the presence of nitro functionality.

Full text of DOI:10.1080/00397910008087360

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Efficient Reduction of
Aryl Azides and Aryl Nitro
Compounds to Their
Corresponding Amines
with Sulfurated Calcium
Borohydride CA(BH S ) . A New
2
3 2
Modified Borohydride Agent
a
a
a
H. Firouzabadi , B. Tamami & A. R. Kiasat
a
Chemistry Department , College of Science, Shiraz
University , Shiraz, 71454, Iran
Published online: 04 Dec 2007.
To cite this article: H. Firouzabadi , B. Tamami & A. R. Kiasat (2000) Efficient
Reduction of Aryl Azides and Aryl Nitro Compounds to Their Corresponding Amines
with Sulfurated Calcium Borohydride CA(BH S ) . A New Modified Borohydride Agent,
2
3 2
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 30:4, 587-596, DOI: 10.1080/00397910008087360
To link to this article: http://dx.doi.org/10.1080/00397910008087360
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