tert-Butyl Hypoiodite for Deoximation
2829
of 4-methylbenzaldoxime (0.5 g, 3.70 mmol) in carbon tetrachloride (20 mL)
dropwise at room temperature under a stream of nitrogen. The stirring was
continued until the oxime disappeared (TLC). The reaction mixture was
diluted with addition of methylene dichloride and water. The organic layer
was separated, washed with 5% cold sodium thiosulphate solution and
water (50 mL), dried over sodium sulphate, and concentrated to give almost
pure 4-methyl benzaldehyde (0.426 g, 96%).
ACKNOWLEDGMENT
We gratefully acknowledge the UICT for financial support under the UICT
Golden Jubilee Fund.
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