European Journal of Medicinal Chemistry p. 331 - 334 (1996)
Update date:2022-08-17
Topics:
Musso
Boswell
Mehta
Soroko
Burchall
A series of benzamides containing N,N,2-trimethyl-1,2-propane diamine as the amide moiety was synthesized. The compounds were evaluated in the maximal electroshock (MES) and pentylenetetrazol (metrazole, MET) screens for anticonvulsant activity. The 3,5-trifluoromethyl, 3,5-dichloro, and 3-bromo analogues proved to be either equipotent with or more potent than phenytoin.
View More
Contact:--
Address:80G, No.1 Building, Guodu Development Mansion, No. 182 Zhaohui Road, Hangzhou City, Zhejiang Province,China.
Huludao Tianqi Shengye Chemical Co.,Ltd.
Contact:0086 429 2075777
Address:Area B,Shipbuilding Industry Park,Beigang District,Huludao City,Liaoning prov.,China
WEIFANG DERUN CHEMICAL CO.,LTD
Contact:86-536-8956886
Address:weifang
Contact:+44 7958 511245
Address:PO Box 469, Manchester, UK
Shanghai Goyic Pharmaceutical&Chemical Co,. Ltd
Contact:+86-021-60275964
Address:No. 528 ruiqing road
Doi:10.1039/C2969001466b
(1969)Doi:10.1021/acs.macromol.0c00192
(2020)Doi:10.1016/0031-9422(89)80150-5
(1989)Doi:10.1021/ja029040o
(2003)Doi:10.1016/j.molstruc.2017.03.122
(2017)Doi:10.1016/j.bmcl.2013.03.088
(2013)
