OXIDATIVE CLEAVAGE OF α-DIOLS, α-DIONES, α-HYDROXY-KETONES AND α-HYDROXY- AND α-KETO ACIDS WITH CALCIUM HYPOCHLORITE

Article abstract of DOI:10.1016/S0040-4039(00)88578-0

α-Diols, α-diones, α-hydroxy ketones, and α-hydroxy- and α-keto acids are easily cleaved oxidatively with calcium hypochlorite.The reaction is carried out at ambient temperature in aqueous acetonitrile/acetic acid solution.The yields are good to excellent and the products, depending on the starting material, are aldehydes, ketones or acids.